Houston
PREMPRO Lawyer Christian Hill
Let Houston personal injury lawyer Christian Hill fight your Prempro / Premphase personal injury case for you. Houston personal injury lawyer Christian Hill and his legal team at the Houston personal injury law firm Christian Hill and Associates are experienced personal injury lawyers, and will fight your Prempro / Premphase personal injury case for you.
Personal injury law is our specialty at Christian Hill and Associates. We have collected over $100 million for personal injury victims. Having an experienced Houston personal injury lawyer is important, especially when dealing with a difficult case such as Prempro / Premphase.
Houston Personal Injury Lawyer: Prempro / Premphase
Prempro Personal Injury
Prempro, (conjugated estrogens/medroxyprogesterone acetate tablets) Wyeth (website), contains two kinds of hormones: estrogens and a progestin. Adding progestin reduces the risk of endometrial cancer in a woman with a uterus. Wyeth estimates that approximately 5 million U.S. women are taking Premarin and 1.5 million are taking Prempro. Approximately 10 million postmenopausal women are taking some form of estrogen, either alone or in combination with a progestin.
Because Premphase contains the same combination of hormones as Prempro, this document will only refer to Prempro.
Prempro is given to postmenopausal women with a uterus to:
* reduce hot flashes
* treat vaginal dryness, itching, and burning
* help reduce chances of getting osteoporosis (thin weak bones)
Some major points have arisen from a Women's Health Initiative (WHI) stud, these are:
* Postmenopausal women should not take estrogen and progestin to protect
the heart.
* Estrogens and progestins may increase the risk of heart attack, stroke,
blood clots and breast cancer.
* Although other doses of Prempro and other estrogens and progestins
were not studied, postmenopausal women who take estrogens and progestins
should also be warned about potential risks, which must be presumed
to be the same.
* When these drugs are being prescribed only to prevent osteoporosis,
other treatments should be considered before prescribing estrogen or
estrogen with progestin.
* Estrogens and estrogens with progestins should be used at the lowest
dose for the shortest duration.
The study results show that of every 10,000 women per year taking Prempro, there would be:
* 8 more cases of breast cancer
* 7 more cases of heart attacks
* 8 more cases of stroke
* 18 more cases of blood clots in the lungs and leg
Some side effects of estrogens and progestins:
Less common but serious side effects include:
* Breast cancer
* Uterine cancer
* Stroke
* Heart attack
* Blood clots
* Gallbladder disease
* Ovarian cancer
Common side effects include:
* Headache
* Breast pain
* Irregular vaginal bleeding or spotting
* Stomach cramps
* Nausea and vomiting
* Hair loss
Specific study findings for the estrogen plus progestin group compared
to placebo include:
* A 41 percent increase in strokes
* A 29 percent increase in heart attacks
* A doubling of rates of venous thromboembolism (blood clots)
* A 22 percent increase in total cardiovascular disease
* A 26 percent increase in breast cancer
* A 37 percent reduction in cases of colorectal cancer
* A one-third reduction in hip fracture rates
* A 24 percent reduction in total fractures
* No difference in total mortality (of all causes)
These are not all the possible side effects of Premarin or Prempro.
For more information, a health care provider or pharmacist should be
consulted.
Long-term risks of Prempro in postmenopausal women include increased risks of breast cancer and thromboembolic disease associated with estrogen and combination estrogen/progestin therapy, as well as increased risk of cardiovascular disease, including myocardial infarction and stroke, in healthy women. (more)
Prempro Links
Prempro Product Information (website)
Wyeth " Prempro manufacturer (website)
NHLBI Stops Trial of Estrogen Plus Progestin Due to Increased Breast Cancer Risk, Lack of Overall Benefit (here) or (here)
Systematic Evidence Reviews from the U.S. Preventive Services Task Force
JAMA article on Risks and Benefits of Estrogen Plus Progestin in Healthy Postmenopausal Women (concerns Prempro Hormone Replacement Therapy, Wyeth Ayerst, Philadelphia, Pa) (here)
Profile of the Estrogen Plus Progestin Component of the Women's Health Initiative chart (click here)
frequently asked questions about the Women's Health Initiative Estrogen Plus Progestin Study (here)
Questions and Answers for Estrogen and Estrogen with Progestin Therapies for Postmenopausal Women
Facts About Postmenopausal Hormone Therapy
NIH Postmenopausal Hormone Therapy
The Office on Women's Health, U.S. Department of Health and Human Services Office: The National Women's Health Center
FDA Office of Women's Health
FDA Fact Sheet: New Advice to Postmenopausal Women
FDA Orders Warning on All Estrogen Labels
Results of WHI Prempro StudyMenopausal Hormone Therapy
Suit filed against maker of hormone replacement drug
Mary Tyler Moore's public service announcement about the dangers of Premarin and Prempro (requires Real Player, click here for video)
Don't Be A Personal Injury Victim
If you have suffered a personal injury from one of these products, it's important to protect your rights. Contact a Houston personal injury lawyer as soon as possible. A personal injury lawyer at Houston law firm Christian Hill and Associates will evaluate your personal injury case at no cost to you. If we determine you have a personal injury claim, we will handle your case aggressively, and you pay absolutely nothing unless we win your personal injury case.
Act Now To Protect Your Rights
Your personal injury case is subject to the statute of limitations. If you don't act now you may lose your right to compensation for the personal injury you have sustained. Contact Houston personal injury lawyer Christian Hill at the law firm of Christian Hill and Associates as soon as possible.
